RECENT RELATED PUBLICATIONS:

1. Sufan Chien: Metabolic management. In: Luis Toledo-Pereyra: Organ Procurement and Preservation for Transplantation, 3rd edition. 82-123. Landes Bioscience Springer, New York, 2008 (URL: http://eurekah.com/chapter/3992).

 

2. Sufan Chien: Intracellular ATP delivery using highly fusogenic liposomes. Methods in molecular Biology. 605:377-391, 2010. PMID: 20072895. 

 

3. Jianpu Wang, Rong Wan, Yiqun Mo, Ming Li, Qunwei Zhang, Sufan Chien,: Intracellular delivery of ATP enhanced healing process in full-thickness skin wounds in diabetic rabbits. American Journal of Surgery, 199: 823-832, 2010. PMID: 20609726.

 

4. Jianpu Wang, Rong Wan, Yiqun Mo, Ming Li, Qunwei Zhang, Sufan Chien: Creating a long-term diabetic rabbit model. Experimental Diabetic Research, 2010: 1-10. PMID: 21234414.

 

5. Jianpu Wang, Rong Wan, Yiqun Mo, Ming Li, Qunwei Zhang, Sufan Chien: Creating a long-term diabetic rabbit model. Experimental Diabetic Research, 2010: 1-10. PMID: 21234414.

 

6. Sufan Chien, Brandon J. Wilhelmi: A simplified technique for producing an ischemic wound model. J Vis Exp. 2012 May 2;(63). pii: 3341. doi:10.3791/3341. PMID: 22588601.

 

7. Wheeler TJ, Chien S.: Protection of rat cardiac myocytes by fructose-1,6-bisphosphate and 2,3-butanedione. PLoS One. 2012;7(4):e35023. Epub 2012 Apr 27. PMID: 22558110.

 

8. Wheeler TJ, Chien S.: Characterization of the high-affinity uptake of fructose-1,6-bisphosphate by cardiac myocytes. Mol Cell Biochem. 2012 Jul;366(1-2):31-9. doi: 10.1007/s11010-012-1279-x. PMID: 22426779.

 

9. Jeffrey D. Howard, Harshini Sarojini, Rong Wan, Sufan Chien: Rapid granulation tissue regeneration by intracellular ATP delivery—a comparison with Regranex. PLOS One, 2014; 9(3): e91787, Mar 17, doi: 10.1371/journal.pone.0091787, PIMD: 24637626.

 

10. Girish Kotwal, Harshini Sarojini, Sufan Chien: Pivotal role of ATP in Macrophages fast tracking wound repair and regeneration. Wound Repair Regeneration. 2015 Sep;23(5):724-7. doi: 10.1111/wrr.12323. PMID: 26053302

 

11. Girish J. Kotwal, Sufan Chien: Macrophage Differentiation in Normal and Accelerated Wound Healing. Results Probl Cell Differ. 2017;62:353-364. doi: 10.1007/978-3-319-54090-0_14. PMID: 28455716.

 

12. Harshini Sarojini, Adrian T Billeter, Rong Wan, Sarah Eichenberger, Devin Druen, Rebecca Barnett, Sarah A Gardner, Norman J Galbraith, Hiram C Polk Jr., Sufan Chien: Rapid tissue regeneration induced by intracellular ATP delivery-A preliminary mechanistic study. PLoS One. 2017 Apr 5;12(4):e0174899. doi: 10.1371/journal.pone.0174899. eCollection 2017. 

 

13. Kotwal GJ, Martin MD, Chien S.: Significant upregulation of U1 and U4 spliceosomal snRNAs by ATP nanoliposomes explains acceleration of wound healing, due to increased pre-mRNA processing to functional mRNA. Nanomedicine. 2018 Apr 5;14(4):1289-1299. doi: 10.1016/j.nano.2018.03.003. PMID: 29627519

 

14. Mo Y, Sarojini, H, Wan, R, Zhang Q, Wang J. Eichenberger SE, Kotwal GJ and Chien S.: Intracellular ATP delivery causes rapid tissue regeneration via upregulation of cytokines, chemokines and stem cells. Front. Pharmacol. 16 January 2020, https://doi.org/10.3389/fphar.2019.01502

 

15. Sarojini H, Bajorek A, Wan R, Wang J, Zhang Q, Billeter AT, Chien S.: Enhanced Skin Incisional Wound Healing With Intracellular ATP Delivery via Macrophage Proliferation and Direct Collagen Production. Front Pharmacol. 2021 Jun 16;12:594586. doi: 10.3389/fphar.2021.594586. PMID: 34220491.

 

 

 

 

 

 

 

MEETING PRESENTATIONS

 

  1. Harshini Sarojini. (August, 2011) Organ Damages in Long Term Diabetic Rabbits. The Price Institute of Surgical Research Seminar presented at Price Institute of Surgical Research, Department of Surgery, University of Louisville, Kentucky
  2. Jeffrey Howard, Harshini Sarojini and Sufan Chien. (October, 2011) Comparison of the efficacy of Regranex and ATP-encapsulated lipid vesicles in skin wound. Poster presented at Research Louisville, University of Louisville, Kentucky
  3. Harshini Sarojini, Adrian T Billeter, Devin Druen, Rong Wan, Sarah A Gardner and Sufan Chien. (September, 2012) Alternative Activation of Macrophages enhances Wound Healing. Poster presented at Research Louisville, University of Louisville, Kentucky.
  4. Harshini Sarojini, Rong Wan, and Sufan Chien (May 17, 2012). A new treatment for chronic wounds. Poster presented at 17th Kentucky NSF-EPSCOR Annual meeting, Lexington, Kentucky.
  5. Rong Wan, Harshini Sarojini, Qunwei Zhang and Sufan Chien (May 17, 2012). Fast tissue regeneration by intracellular energy delivery. Poster presented at 17th Kentucky NSF-EPSCOR Annual meeting, Lexington, Kentucky.
  6. Rong Wan, Harshini Sarojini, Qunwei Zhang and Sufan Chien. (April, 2012) A New Form of Tissue Regeneration. Poster presented at the 22nd Wound Healing Society meeting at Atlanta, Georgia.
  7. Jeffrey Howard, Harshini Sarojini and Sufan Chien (April, 2012) Efficacy of Intracellular ATP delivery in skin wound healing- A comparison with Regranex. Poster presented at the 22nd Wound Healing Society meeting at Atlanta, Georgia.
  8. Harshini Sarojini, Jeffrey Howard, Rong Wan, Qunwei Zhang and Sufan Chien. (October, 2011) Severe Organ Damages in Long Term Diabetic Rabbits. Poster presented at Research Louisville, University of Louisville, Kentucky
  9. Harshini Sarojini, Sarah Eichenberger, Siow Yong, Cuibo Yang, and Sufan Chien.(October, 2013) Macrophage In situ proliferation by intracellular ATP delivery promotes faster wound healing. Accelerating Acute Wound Healing Via Alternative Pathway Sufan Chien, Harshini Sarojini, Siow Yong, Cuibo Yang.(October, 2013) Intracellular energy delivery for hemorrhagic. Poster presented at 18th Kentucky NSF-EPSCOR Annual meeting, Louisville, Kentucky.
  10. Harshini Sarojini, Sarah Eichenberger, Siow Yong, Cuibo Yang, and Sufan Chien. (September, 2013) A New Pathway for Fast Tissue Regeneration. Poster presented at Research Louisville, University of Louisville, Kentucky.
  11. Harshini Sarojini, Rong Wan, Adrian T Billeter, Devin Druen, Sarah A Gardner and Sufan Chien. (May 2013). Enhanced collagen production by macrophages. Poster presented at the 23rd Wound Healing Society meeting at Denver, Colarado.
  12. Sufan Chien, Harshini Sarojini, Rong Wan and Qunwei Zhang (May 2013). Mechanisms of a single phase tissue regeneration. Poster presented at the 23rd Wound Healing Society meeting at Denver, Colarado.
  13. Harshini Sarojini (October, 2013) Macrophage In situ proliferation by intracellular ATP delivery promotes faster wound healing. Paper presented at 18th Kentucky NSF-EPSCOR Annual meeting, Louisville, Kentucky.
  14. Harshini Sarojini. (May, 2013) Rapid Tissue Regeneration- The role of macrophages. The Price Institute of Surgical Research Seminar presented at Price Institute of Surgical Research, Department of Surgery, University of Louisville, Kentucky
  15. Cuibo Yang, Harshini Sarojini, and Sufan Chien. (September, 2014) Intracellular ATP delivery and Brahma-related gene-1 (BRG1)/Brm gene expression in accelerated rabbit wound healing. Poster presented at Research Louisville, University of Louisville, Kentucky
  16. Harshini Sarojini, Sarah Eichenberger, Cuibo Yang, and Sufan Chien. (September, 2014) Elimination of Lag Time in Wound Healing. Poster presented at Research Louisville, University of Louisville, Kentucky
  17. Sufan Chien, Harshini Sarojini, Rong Wan (September, 2014) Intracellular energy delivery enhaces incisional wound healing. Poster presented at 10th Kentucky Innovation and Entrepreneurship Conference. Louisville, Kentucky
  18. Harshini Sarojini, Adrian T Billeter, Devin Druen, Sarah Eichenberger, Siow Yong, Cuibo Yang, Hiram C Polk Jr., and Sufan Chien (October 2014). In situ macrophage proliferation changes wound healing process. Paper presented at the 100th Clinical Congress of the American College of Sugeons. San Francisco, California.
  19. Harshini Sarojini. (March, 2014) Molecular methods involved in a novel method of fast tissue regeneration. The Price Institute of Surgical Research Seminar presented at Price Institute of Surgical Research, Department of Surgery, University of Louisville, Kentucky
  20. Harshini Sarojini, Sarah Eichenberger, Cuibo Yang, and Sufan Chien. (September, 2014) Elimination of Lag Time in Wound Healing. Poster presented at 10th Kentucky Innovation and Entrepreneurship Conference. Louisville, Kentucky
  21. Harshini Sarojini, Cuibo Yang, Girish Kotwal and Sufan Chien. (May 2015). Fast track healing of acute wounds. Paper presented at the 25th Wound Healing Society Meeting. San Antonio, Texas.
  22. Harshini Sarojini (January, 2015) Elimination of Lag time in wound healing. Invited Lecture Department of Zoology, University College, Palayam, Thiruvananthapuram.
  23. Harshini Sarojini, Cuibo Yang, and Sufan Chien. (October, 2015) Cellular Mechanism of Wound Healing in ATP-Vesicle Treated Diabetic Wounds. Poster presented at Research Louisville, University of Louisville, Kentucky
  24. Harshini Sarojini, Cuibo Yang and Sufan Chien,(May 2015) Accelerating Acute Wound Healing Via Alternative Pathway Poster presented at 2015 Kentucky NSF-EPSCOR Annual meeting, Lexington, Kentucky.
  25. Cuibo Yang, Harshini Sarojini, Sufan Chien (May 2015) Chromatin Remodeling Complex Activation Results In Rapid In Situ Macrophage Proliferation In Wound Healing. Poster presented at 2015 Kentucky NSF-EPSCOR Annual meeting, Lexington, Kentucky.
  26. Cuibo Yang, Harshini Sarojini, and Sufan Chien (May 2015) Chromatin remodeling complex activation results in rapid in situ macrophage proliferation in wound healing. Poster presented at the 25th Wound Healing Society Meeting. San Antonio, Texas.
  27. Harshini Sarojini, Cuibo Yang, and Sufan Chien (April 2016) ATP-vesicle treatment induced macrophage M2 polarization accelerates skin wound healing. Paper presented at the 26th Wound Healing Society Meeting. Atlanta, Georgia
  28. Harshini Sarojini, Sarah Eichenberger, and Sufan Chien. (October, 2016) Intracellular ATP Delivery Induces Macrophage Polarization and Direct Collagen Production for Faster Wound Healing. Poster presented at Research Louisville, University of Louisville, Kentucky
  29. Cuibo Yang, Yuting Zheng, Harshini Sarojini, Sufan Chien (April 2016) Intracellular ATP delivery induced rapid tissue regeneration is accompanied by upregulation of nuclear transcription factors PPARΑ, PPARΒ, PGC1α and prolidase   Poster presented at the 26th Wound Healing Society Meeting. Atlanta, Georgia
  30. Sufan Chien and Harshini Sarojini (October, 2016) Insitional wounds Ischemia and treatment. Poster presented at Research Louisville, University of Louisville, Kentucky
  31. Harshini Sarojini, Sarah Eichenberger, and Sufan Chien (December 2017) Intracellular ATP delivery treatment enhances wound healing by elimination of the lag time. Paper presented in the 4th Annual Innovations in Wound Healing Meeting in Bimini, Bahamas.
  32. Harshini Sarojini (September 2017) Wound Healing Research- From bench to bedside. Invited Lecture Department of Biochemistry, University of Kerala, Karyavattom, Thiruvananthapuram.
  33. Harshini Sarojini, Sarah Eichenberger, and Sufan Chien (April 2017) Macrophage In situ proliferation, M2 polarization and direct collagen synthesis—a new pathway for faster wound healing. Paper presented at the 27th Wound Healing Society Meeting. San Diego, California.
  34. Harshini Sarojini, Sarah Eichenberger, and Sufan Chien (December 2017) Intracellular ATP delivery treatment enhances wound healing by elimination of the lag time. Paper presented in the 4th Annual Innovations in Wound Healing Meeting in Bimini, Bahamas.
  35. Arezoo Rajaee, Harshini Sarojini, Sarah Eichenberger, and Sufan Chien. (September, 2017) Generation of an Extremely Long Ischemic Wound Model. Poster presented at Research Louisville, University of Louisville, Kentucky
  36. Arezoo Rajaee Harshini Sarojini and Sufan Chien. (April, 2018) Comparison of noninvasive skin perfusion techniques. Poster presented at the 28th Wound Healing Society Meeting. Charlotte, North Carolina.
  37. Arezoo Rajaee Harshini Sarojini, Sarah Eichenberger, Stephen O’Brien, Michael Martin and Sufan Chien. (April, 2018) Generation of an extremely long term ischemic wound model. Poster presented at the 28th Wound Healing Society Meeting. Charlotte, North Carolina.
  38. Sufan Chien and Harshini Sarojini (April, 2018) Incisional wounds ischemia and treatment. Poster presented at the 28th Wound Healing Society Meeting. Charlotte, North Carolina.
  39. Harshini Sarojini, Sarah Eichenberger, Arezoo Rajaee and Sufan Chien. (April, 2018) Intracellular ATP delivery induces enhanced wound healing via early initiation of the wound healing cascade. Poster presented at the 28th Wound Healing Society Meeting. Charlotte, North Carolina.
  40. Harshini Sarojini (April 2019) Ischemia and Wound healing. Cardiovascular Innovation Institute seminar presented at Cardiovascular Innovation Institute, University of Louisville, Kentucky.
  41. Sufan Chien, Harshini Sarojini , Girish Kotwal, Mohammad Bayat, and Sarah Eichenberger (September, 2019) A new model for chronic wounds. Poster presented at Research Louisville, University of Louisville, Kentucky
  42. Harshini Sarojini, Sarah Eichenberger, and Sufan Chien. (September, 2019) Development of a Biomarker for Chronic Wounds. Poster presented at Research Louisville, University of Louisville, Kentucky
  43. Harshini Sarojini, Sarah Eichenberger and Sufan Chien (July 2020) Wound healing macrophages: the intervention of ATP to stimulate pro-wound healing phenotypes. Paper presented at the 30th   Wound Healing Society Meeting. (Virtual Presentation).
  44. Harshini Sarojini and Sufan Chien (July 2021) Intracellular ATP delivery induced rapid skin incisional wound healing via macrophage proliferation and direct collagen production. Keynote speech at the 2nd   Edition of Webinar on Pharmaceutical Technology and Drug Discovery.  (Virtual Presentation).
  45. Harshini Sarojini, Sarah Eichenberger and Sufan Chien (February 2021) Extremely rapid tissue regeneration caused by Intracellular ATP delivery. Paper presented at the 3rd   Pharmscience Research and Development Conference. (Virtual Presentation).

 

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